C&EN e-book
Pure mRNA: Downstream processing strategies for an emerging modality
Brought to you by Thermo Fisher Scientific
Overview

According to industry experts, the purification step is absolutely essential to the commercialization of any mRNA therapeutic. As the field of mRNA therapeutics advances, there is now a growing focus on refining, optimizing, and standardizing manufacturing processes, particularly the downstream processing steps. This phase is crucial for ensuring that any mRNA product is pure, stable, and effective.

Key differences between mRNA and more traditional biologics necessitate specialized purification methods to remove impurities and meet still-emerging quality standards. The efficiency and scalability of these processes could make or break the successful commercialization of current and future mRNA therapies. Download this resource to stay on the cutting edge of mRNA therapeutic development and manufacturing.

Key Objectives:
  • Establish the importance of mRNA purification
  • Explore challenges unique to this new modality
  • Examine the range of purification tools available to current or aspiring manufacturers of mRNA therapeutics

Brought to you by:
Thermo Fisher Scientific
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