Recent Biopharmaceutical Chromatographic Advances

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Overview

The chromatographic applications include purification and analysis of VLPs and antibody drugs, LC/MS and HILIC analysis of oligonucleotides, amino acids and other proteins. The initial proof of concept of these biopharmaceutical applications displays recent advances in this growing field.

Key Objectives：

Norovirus VLP were purified from silkworms and investigated as a proof of concept
LC/MS analysis of various oligonucleotides were studied without the use of an ion-pair reagent
Additives and aggregates in antibody drugs were isolated using simple methods
Choline, acetylcholine, neurotransmitters, oral antidiabetic drugs and aminoglycoside antibiotics were analyzed on a single column

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