Ensuring Precision and Efficiency in Pharmaceutical Color Assessment: Variable Pathlength Technology Multiattribute Approach Under EP 2.2.2

Ensuring Precision and Efficiency in Pharmaceutical Color Assessment: Variable Pathlength Technology Multiattribute Approach Under EP 2.2.2

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Overview

A thorough look into color assessment in the pharmaceutical field, this paper explores current colorimetric methods and compares color measurements of a single-pathlength colorimeter to the multiattribute approach of variable pathlength technology (VPT), according to European Pharmacopoeia (EP) Chapter 2.2.2 guidelines.

Key Objectives:

Reducing the variability of typical color assessment methods within pharmaceutical development and quality control
Evaluating the challenges and disadvantages of measuring color using single-pathlength colorimeters, visual perception, and multiattribute approaches
Exploring how color assessment with analytical testing is achieved through variable pathlength technology (VPT) and its slope regression measurements

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