C&EN White Paper
Better, faster small-molecule synthesis: leveraging modern tools to evaluate and optimize process chemistry
Brought to you by Lonza
Overview

Small-molecule APIs are becoming increasingly complex, with new drug modalities requiring more synthetic steps than ever before. Developing your synthetic route has become more time-consuming and resource-intensive, which can delay getting your medicine into the market.

Advanced technologies, such as Lonza’s AI-enabled route scouting tool, high-throughput experimentation (HTE) equipment, and the Design2Optimize™ platform, allow you to optimize your method faster. Learn how these systems operate and how they work together to streamline your development.

Key Objectives:
  • How computer-aided synthesis planning (CASP) tools use supply chain data to identify optimal synthetic pathways.
  • Application of how high-throughput experimentation accelerates the identification of optimal synthesis pathways.
  • Introduction to Design2Optimize™, Lonza’s physicochemical-intelligent approach to experimental design.
Our Experts:

Jens Schmidt
Associate Director of Manufacturing, Science, and Technology,
Lonza Advanced Synthesis

Charles Johnson
Senior Director of Commercial Development,
Lonza Advanced Synthesis

Nichola McCann
Senior Principle Scientist of Process Technologies and Innovation,
Lonza Advanced Synthesis

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