Peptide Crystallization: A Scalable Solution in Pharmaceutical Process Development

DATE

July 29, 2026

TIME

8:00 a.m. PDT, 11:00 a.m. EDT, 16:00 BST, 17:00 CEST - Duration: 60 Minutes

Overview

The molecular complexity of peptides may have kept them out of development pipelines in the past, but innovations in synthesis and purification have fueled their recent momentum as alternatives to traditional small molecules to address unmet medical needs. Integrating crystallization into the development and manufacture of peptides can address key challenges, allowing for significant impurity rejection, improved processability, increased stability, full structural determination, and lower overall cost when compared to column chromatography methods for purification.

Join Cambrex expert Hannah McLachlan for a live webinar as she explores these benefits in the crystallization of peptide fragments, as well as whole peptide compounds. She will also discuss how the team at Cambrex’s Edinburgh facility has recently developed a high throughput screening approach to initial crystallization screening for peptide fragments.

Key Learning Objectives:

Advantages of peptide crystallization
Technical differences in crystallizing peptide fragments compared to whole peptide compounds
Advantages and disadvantages of high throughput screening techniques
Case studies showing:
Improvements in peptide characteristics following crystallization
How successful results in the crystallization of peptide fragments can be utilized to direct trials for screening of the complete peptide
How high throughput screening can save time and give guidance on further development work
The effects of scale on purity uplift

Who Should Attend:

Research and Development
CMC (Chemistry, Manufacturing, and Controls)
Process Development
Pharmaceutical Manufacturing

Brought to you by:

Speakers

Hannah McLachlan, Ph.D.
Team Leader – Crystallization,
Cambrex

Alexandra Taylor
Contributing Editor,
ACS Media Group

Registration

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