Real-Time, Dilution-Free Concentration Measurement Using Variable Pathlength Spectroscopy for Biopharmaceutical Workflows

DATE

February 25, 2025

TIME

8:00 a.m. PST, 11:00 a.m. EST, 16:00 GMT, 17:00 CET - Duration: 60 Minutes

Overview

The biopharmaceutical industry is increasingly focused on developing higher drug concentration formulations to improve efficiency, reduce production costs, and meet the growing demands for more potent biologics. As the industry shifts toward more concentrated biologics, there is an urgent need for more efficient and reliable analytical tools to measure concentrations at all stages of production, from process development to manufacturing and release testing.

Traditional UV/Vis spectroscopy methods, which rely on fixed pathlengths, face significant challenges when dealing with highly concentrated or limited volume samples, often requiring time-consuming dilution steps. With the growing demand for faster, more accurate results in these increasingly complex workflows, the ability to measure high concentrations quickly and accurately has become a critical need.

In this webinar, we will introduce the new CTech™ SoloVPE® PLUS, which utilizes variable pathlength technology (VPT) to enable dilution-free, real-time concentration measurements across a wide range of analytes. We will discuss how this emerging technology addresses the industry's evolving needs for more accurate, faster testing to support the development and release of mRNA-based therapeutics, monoclonal antibodies, and other biologic products. You’ll also learn how VPT can accelerate decision-making, improve productivity, and enhance efficiency in process development, manufacturing, and release testing workflows.

Key Learning Objectives:

Understand the challenges posed by traditional UV/Vis spectroscopy methods for highly concentrated or limited volume samples.
Learn how variable pathlength technology enables dilution-free, real-time concentration measurement for complex biologics workflows.
Gain insight into how emerging technologies are addressing the industry's evolving demands for higher concentration formulations and faster testing

Who Should Attend:

This webinar is ideal for professionals working in biopharmaceutical workflows, including:

Process Development Scientists
Analytical Development Scientists
Quality Control and Quality Assurance Scientists
Manufacturing Science and Technology (MSAT) Scientists

Brought to you by:

Speakers

Joe Ferraiolo
Director, Bioanalytics Applications,
Repligen

Kelly McSweeney
Contributing Editor,
C&EN Media Group

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The CTech SoloVPE PLUS System uses patented variable pathlength technology to accurately measure various targeted concentrations. Would you like a Repligen analytics specialist to contact you to learn more about variable pathlength spectroscopy and its role in accelerating biopharmaceutical workflows?*

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