Beyond the Method: Uncovering the Limits of PFAS Detection with Combustion Ion Chromatography

DATE

August 13, 2025

TIME

10:00 a.m. PDT, 1:00 p.m. EDT, 18:00 BST, 19:00 CEST

Overview

As regulatory attention on PFAS intensifies, laboratories are seeking more comprehensive detection strategies. While LC-MS/MS remains the gold standard for targeted PFAS analysis, it doesn't tell the full story. Combustion Ion Chromatography (CIC) offers a powerful, complementary approach, helping labs assess broad-spectrum organofluorine content through AOF and EOF testing.

This webinar explores recent studies by Babcock Laboratories in collaboration with the California State Water Resources Control Board, using Metrohm’s Profiler-F to push the boundaries of PFAS detection. The presentation will cover method development across challenging matrices such as drinking water, address issues like background fluorine and blank subtraction, and highlight sample preparation limitations and analyte recovery. Attendees will also gain insight into how EOF testing is being explored as a future alternative to AOF, with the potential to overcome key analytical challenges.

Whether you're new to CIC or looking to refine existing workflows, this session offers practical, real-world guidance for expanding your lab’s PFAS testing capabilities.

Stick around for a live Q&A with PFAS experts David Schiessel (Babcock Laboratories) and Dr. Jay Gandhi (Metrohm USA).

Key Learning Objectives:

How to develop CIC methods for AOF and EOF across different matrices, including drinking water
Strategies to address common challenges such as background fluorine and sample preparation limitations
Best practices for blank subtraction and improving analyte recovery
Insights into the evolving role of EOF in long-term PFAS

Who Should Attend:

Scientists and lab managers performing or evaluating PFAS analysis by CIC
Labs exploring AOF/EOF methods for non-targeted fluorine detection
Regulatory or method development professionals working with drinking water or environmental matrices

Brought to you by:

Speakers

David Schiessel
Technical Manager, Organics Department
Babcock Laboratories Inc.

Dr. Jay Gandhi
Vertical Market Manager
Metrohm USA

Melissa O'Meara
Forensic Science Consultant
C&EN Media Group

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